Phenotypes associated with this allele

• Allele Symbol: Lrpap1^tm1Vln
• Allele Name: targeted mutation 1, Fred Van Leuven
• Allele ID: MGI:4366260
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lrpap1^tm1Vln/Lrpap1^tm1Vln	B6.129P2-Lrpap1^tm1Vln	MGI:4366262
hm2	Lrpap1^tm1Vln/Lrpap1^tm1Vln	involves: 129P2/OlaHsd * C57BL/6	MGI:4366261

Genotype
MGI:4366262

hm1

• Allelic Composition: Lrpap1^tm1Vln/Lrpap1^tm1Vln
• Genetic Background: B6.129P2-Lrpap1^tm1Vln

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

mortality/aging ( J:107547 )

N • adults are healthy and active up to 2 years of age

postnatal lethality, incomplete penetrance ( J:107547 )

• poorer survival of pups over the first few days of life

reproductive system

decreased litter size ( J:107547 )

• Background Sensitivity: reduced litter size seen in congenic mice on a C57BL/6 background

• litter size at E18 is normal

Genotype
MGI:4366261

hm2

• Allelic Composition: Lrpap1^tm1Vln/Lrpap1^tm1Vln
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

mortality/aging

mortality/aging ( J:107547 )

N • adults are healthy and active up to 2 years of age

reproductive system

reproductive system phenotype ( J:107547 )

N • Background Sensitivity: normal litter size