Phenotypes associated with this allele

• Allele Symbol: Gt(ROSA)26Sor^tm6Dym
• Allele Name: targeted mutation 6, Susan Dymecki
• Allele ID: MGI:4366498
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Gt(ROSA)26Sor^tm6Dym/? Smo^tm2Amc/Smo^tm2Amc Sox9^tm3(cre)Crm/Sox9^+	involves: 129S7/SvEvBrd * 129X1/SvJ	MGI:4366499

Genotype
MGI:4366499

cn1

• Allelic Composition: Gt(ROSA)26Sor^tm6Dym/?; Smo^tm2Amc/Smo^tm2Amc; Sox9^tm3(cre)Crm/Sox9⁺
• Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

small mandibular condyloid process ( J:153743 )

• at E17.5, the temporomandibular condyle is much smaller in size with loss of growth plate organization unlike in wild-type mice

abnormal temporomandibular joint morphology ( J:153743 )

• the temporomandibular joint forms in close proximity to the condyle resulting in an absence of the lower joint cavity unlike in wild-type mice

craniofacial

small mandibular condyloid process ( J:153743 )

• at E17.5, the temporomandibular condyle is much smaller in size with loss of growth plate organization unlike in wild-type mice

abnormal temporomandibular joint morphology ( J:153743 )

• the temporomandibular joint forms in close proximity to the condyle resulting in an absence of the lower joint cavity unlike in wild-type mice