Analysis Tools|
Allele Symbol Allele Name Allele ID |
Prdm1tm1.1Liz targeted mutation 1.1, Elizabeth K Bikoff MGI:4366868 |
||||||||||||
| Summary |
2 genotypes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• LPS-stimulated splenocytes exhibit a 90% decrease in IgM secretion compared with similarly treated wild-type mice
|
|
• LPS-stimulated splenocytes exhibit a 90% decrease in IgM secretion compared with similarly treated wild-type mice
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• 12 of 13 mice exhibit germ cell defects
|
 |
• testes lack spermatocytes
|
|
• slightly at E9.5
|
|
• although normally represented at E10.5, fewer than expected mice are present at E14.5
|
|
• fewer than expected mice are found at weaning
|
|
• 12 of 13 mice exhibit germ cell defects
|
|
|
• testes lack spermatocytes
|
|
• slightly at E9.5
|
|
• mice exhibit a rudimentary or missing fifth digit on the forelimb unlike wild-type mice
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/12/2024 MGI 6.24 |
|
|
|
||
