Analysis Tools|
Allele Symbol Allele Name Allele ID |
Prdm1tm1.1Liz targeted mutation 1.1, Elizabeth K Bikoff MGI:4366868 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• LPS-stimulated splenocytes exhibit a 90% decrease in IgM secretion compared with similarly treated wild-type mice
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• LPS-stimulated splenocytes exhibit a 90% decrease in IgM secretion compared with similarly treated wild-type mice
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 12 of 13 mice exhibit germ cell defects
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• testes lack spermatocytes
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• slightly at E9.5
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• although normally represented at E10.5, fewer than expected mice are present at E14.5
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• fewer than expected mice are found at weaning
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• 12 of 13 mice exhibit germ cell defects
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• testes lack spermatocytes
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• slightly at E9.5
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• mice exhibit a rudimentary or missing fifth digit on the forelimb unlike wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/24/2024 MGI 6.24 |
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