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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Scn9atm1.1Naas
targeted mutation 1.1, Nanda A Singh
MGI:4367789
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Scn9atm1.1Naas/Scn9atm1.1Naas B6.129-Scn9atm1.1Naas MGI:4367796
hm2
Scn9atm1.1Naas/Scn9atm1.1Naas involves: 129S1/Sv * 129X1/SvJ * C57BL/6J MGI:4367795


Genotype
MGI:4367796
hm1
Allelic
Composition
Scn9atm1.1Naas/Scn9atm1.1Naas
Genetic
Background
B6.129-Scn9atm1.1Naas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn9atm1.1Naas mutation (0 available); any Scn9a mutation (121 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice exhibit faster kindling acquisition rate compared with similarly treated wild-type mice

nervous system
• mice exhibit faster kindling acquisition rate compared with similarly treated wild-type mice




Genotype
MGI:4367795
hm2
Allelic
Composition
Scn9atm1.1Naas/Scn9atm1.1Naas
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn9atm1.1Naas mutation (0 available); any Scn9a mutation (121 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice subjected to corneal electrical stimulation exhibit lower thresholds to minimal clonic and minimal tonic hind limb extension compared with similarly treated wild-type mice
• however, mice do not exhibit spontaneous seizures
• mice subjected to corneal electrical stimulation exhibit lower thresholds to minimal clonic compared with similarly treated wild-type mice

nervous system
• mice subjected to corneal electrical stimulation exhibit lower thresholds to minimal clonic and minimal tonic hind limb extension compared with similarly treated wild-type mice
• however, mice do not exhibit spontaneous seizures
• mice subjected to corneal electrical stimulation exhibit lower thresholds to minimal clonic compared with similarly treated wild-type mice





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory