reproductive system
N |
• female mice exhibit normal ovary morphology and fertility
|
• at 5 months, male mice exhibit a depletion of meiotic cells, post-meiotic cells, and mature sperm cells compared with wild-type mice
|
• beginning at P14 and more prevalent at P18
|
• at leptotene with increased staining for double strand breaks
|
• beginning at P14 and more prevalent at P18
|
small testis
(
J:154374
)
|
• despite normal copulation
|
endocrine/exocrine glands
small testis
(
J:154374
)
|
cellular
• at 5 months, male mice exhibit a depletion of meiotic cells, post-meiotic cells, and mature sperm cells compared with wild-type mice
|
• beginning at P14 and more prevalent at P18
|
• at leptotene with increased staining for double strand breaks
|
• beginning at P14 and more prevalent at P18
|