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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tfap2etm1(cre)Will
targeted mutation 1, Trevor Williams
MGI:4398845
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Tfap2etm1(cre)Will/Tfap2etm1(cre)Will involves: 129S1/Sv * Black Swiss MGI:4398856


Genotype
MGI:4398856
hm1
Allelic
Composition
Tfap2etm1(cre)Will/Tfap2etm1(cre)Will
Genetic
Background
involves: 129S1/Sv * Black Swiss
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tfap2etm1(cre)Will mutation (0 available); any Tfap2e mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• at P14, the inner plexiform layer is absent, mitral cells appear disorganized, and mitral cell layer is slightly expended compared to in wild-type mice
• formation of olfactory bulb neuronal layers is disrupted compared to in wild-type mice
• however, the olfactory circuitry is normal

taste/olfaction
N
• despite defects in olfactory bulb morphology, mice exhibit normal olfaction





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory