Phenotypes associated with this allele

• Allele Symbol: Acvrl1^tm2.2Spo
• Allele Name: targeted mutation 2.2, S Paul Oh
• Allele ID: MGI:4398902
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Acvrl1^tm2.2Spo/Acvrl1^tm2.2Spo	involves: 129 * C57BL/6 * FVB/N	MGI:4398917

Genotype
MGI:4398917

hm1

• Allelic Composition: Acvrl1^tm2.2Spo/Acvrl1^tm2.2Spo
• Genetic Background: involves: 129 * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:130020 )

• mice die at E10.5

embryo

absent vitelline blood vessels ( J:130020 )

• at E9.5

embryonic growth retardation ( J:130020 )

• at E9.5

cardiovascular system

absent vitelline blood vessels ( J:130020 )

• at E9.5

hemorrhage ( J:130020 )

• at E9.5, mice exhibit blood pooling in the head and tail regions unlike wild-type mice

growth/size/body

embryonic growth retardation ( J:130020 )

• at E9.5