Phenotypes associated with this allele

• Allele Symbol: Rnf103^tm1.1Thg
• Allele Name: targeted mutation 1.1, Tamotsu Hashimoto-Gotoh
• Allele ID: MGI:4410507
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rnf103^tm1.1Thg/Rnf103^tm1.1Thg	B6N.129-Rnf103^tm1.1Thg	MGI:4410508

Genotype
MGI:4410508

hm1

• Allelic Composition: Rnf103^tm1.1Thg/Rnf103^tm1.1Thg
• Genetic Background: B6N.129-Rnf103^tm1.1Thg

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

enhanced contextual conditioning behavior ( J:154853 )

• immediate freezing is enhanced following aversive foot shock

increased anxiety-related response ( J:154853 )

• mice exhibit decreased light/dark transitions, reduced stay time in light and travel shorter distances in the light

• in the elevated plus maze, mice exhibit decreased number of entries and total distance travelled

decreased startle reflex ( J:154853 )

• mice show a reduced startle amplitude in startle-stimulus-only trials

impaired coordination ( J:154853 )

• homozygous mice exhibit longer wire-hanging time than controls

nervous system

increased prepulse inhibition ( J:154853 )