Phenotypes associated with this allele

• Allele Symbol: Gsx2^tm2.2Kc
• Allele Name: targeted mutation 2.2, Kenneth Campbell
• Allele ID: MGI:4412067
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gsx2^tm2.2Kc/Gsx2^tm2.2Kc	involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	MGI:4412087

Genotype
MGI:4412087

hm1

• Allelic Composition: Gsx2^tm2.2Kc/Gsx2^tm2.2Kc
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal neuron differentiation ( J:154936 )

• mice exhibit alterations in striatal and olfactory bulb neurogenesis at birth, as determined by marker expression

abnormal telencephalon morphology ( J:154936 )

• mice exhibit the same defects as those observed in Gsx2^tm1Ssp homozygotes

abnormal telencephalon development ( J:154936 )

• mice exhibit abnormalities in dorsal-ventral patterning of the telencephalon as determined by marker expression

• at E12.5, mice exhibit altered expression of pallial markers compared with wild-type mice

decreased striatum size ( J:154936 )

• as determined by marker expression, striatal volume is decreased 57% compared to in wild-type mice

cellular

abnormal neuron differentiation ( J:154936 )

• mice exhibit alterations in striatal and olfactory bulb neurogenesis at birth, as determined by marker expression