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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1.1(CAG-EGFP)Fsh
targeted mutation 1.1, Gordon Fishell
MGI:4412373
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1.1(CAG-EGFP)Fsh/Gt(ROSA)26Sor+
Nkx6-2tm1Qiu/Nkx6-2tm1(cre/ERT2)Fsh 		involves: 129S6/SvEvTac * C57BL/6 * Swiss Webster MGI:4412378


Genotype
MGI:4412378
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1.1(CAG-EGFP)Fsh/Gt(ROSA)26Sor+
Nkx6-2tm1Qiu/Nkx6-2tm1(cre/ERT2)Fsh
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1.1(CAG-EGFP)Fsh mutation (1 available); any Gt(ROSA)26Sor mutation (993 available)
Nkx6-2tm1(cre/ERT2)Fsh mutation (1 available); any Nkx6-2 mutation (17 available)
Nkx6-2tm1Qiu mutation (0 available); any Nkx6-2 mutation (17 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal brain interneuron morphology ( J:155164 )
• following tamoxifen treatment at E12.5, mice exhibit a small and partially penetrant loss of delayed non-fast spiking somatostatin/calretinin double positive cortical interneurons compared with wild-type mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory