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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(tetO-LRRK2*G2019S)1Cai
transgene insertion 1, Huaibin Cai
MGI:4414665
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-LRRK2*G2019S)1Cai/0
Not Specified MGI:4414669


Genotype
MGI:4414669
cx1
Allelic
Composition
Tg(Camk2a-tTA)1Mmay/0
Tg(tetO-LRRK2*G2019S)1Cai/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Camk2a-tTA)1Mmay mutation (8 available)
Tg(tetO-LRRK2*G2019S)1Cai mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• total neurite length is shortened compared to in wild-type mice
• neurons produce fewer neurites than in wild-type mice
• however, doxycyclin or forskolin treatment rescues the inhibited neurite growth
• the longest process corresponding to the axon is reduced in length compared to in wild-type mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory