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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Plec/Parp10tm1.1Gwi
targeted mutation 1.1, Gerhard Wiche
MGI:4414775
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Plec/Parp10tm1.1Gwi/Plec/Parp10tm1.1Gwi involves: BALB/cJ * C57BL/6 MGI:4414791


Genotype
MGI:4414791
hm1
Allelic
Composition		 Plec/Parp10tm1.1Gwi/Plec/Parp10tm1.1Gwi
Genetic
Background		 involves: BALB/cJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plec/Parp10tm1.1Gwi mutation (0 available); any Parp10 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon morphology ( J:155511 )
• the number of small myelinated axons in the phrenic nerves is increased compared to in wild-type mice
decreased nerve conduction velocity ( J:155511 )
• in the sciatic nerve

behavior/neurological
behavior/neurological phenotype ( J:155511 )
N
• despite reduced nerve conduction, mice exhibit normal reflexes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory