Phenotypes associated with this allele

• Allele Symbol: Plekhg5^tm1.1Jbar
• Allele Name: targeted mutation 1.1, Jay Baraban
• Allele ID: MGI:4414815
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plekhg5^tm1.1Jbar/Plekhg5^tm1.1Jbar	involves: 129S1/Sv * 129X1/SvJ	MGI:4414822

Genotype
MGI:4414822

hm1

• Allelic Composition: Plekhg5^tm1.1Jbar/Plekhg5^tm1.1Jbar
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal kidney vasculature morphology ( J:155152 )

• arterial system more sparse as determined by microcomputed tomography

• deficient in small diameter vessels

• major vessels are intact

• volume of arterial trees about 75% of controls

• density of capillaries reduced

abnormal angiogenesis ( J:155152 )

abnormal artery development ( J:155152 )

decreased angiogenesis ( J:155152 )

abnormal coronary vessel morphology ( J:155152 )

• coronary arterial system more sparse as determined by microcomputed tomography

• deficient in small diameter coronary vessels

• major coronary vessels are intact

• volume of coronary arterial trees about 75% of controls

• density of coronary capillaries reduced

renal/urinary system

abnormal kidney vasculature morphology ( J:155152 )

• arterial system more sparse as determined by microcomputed tomography

• deficient in small diameter vessels

• major vessels are intact

• volume of arterial trees about 75% of controls

• density of capillaries reduced