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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ghrtm1.1Jero
targeted mutation 1.1, Jennifer Rowland
MGI:4414833
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Ghrtm1.1Jero/Ghrtm1.1Jero B6.129X1-Ghrtm1.1Jero MGI:4414834
ht2
Ghrtm1.1Jero/Ghr+ B6.129X1-Ghrtm1.1Jero MGI:4414835


Genotype
MGI:4414834
hm1
Allelic
Composition
Ghrtm1.1Jero/Ghrtm1.1Jero
Genetic
Background
B6.129X1-Ghrtm1.1Jero
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ghrtm1.1Jero mutation (0 available); any Ghr mutation (50 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• in male mice at 60 day and 13 months
• at 4 and 13 months, the inguinal subcutaneous fat weight as a percent of body weight is increased compared to in wild-type mice
• in male mice at 13 months

homeostasis/metabolism

growth/size/body
• at 2 months, male and female mice weigh 46% and 50%, respectively, of wild-type mice weight

liver/biliary system
• in male mice at 60 day

nervous system
• in male mice at 60 day

skeleton




Genotype
MGI:4414835
ht2
Allelic
Composition
Ghrtm1.1Jero/Ghr+
Genetic
Background
B6.129X1-Ghrtm1.1Jero
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ghrtm1.1Jero mutation (0 available); any Ghr mutation (50 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• at 6 weeks, mice exhibit reduced body weight compared with wild-type mice
• at 2 months, male and female mice weigh 87% and 86%, respectively, of wild-type mice weight





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory