All Phenotypes Tg(Prnp-cre/ERT)28.8Ics MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Prnp-cre/ERT)28.8Ics
transgene insertion 28.8, Mouse Clinical Institute
MGI:4415180

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ate1^tm1Avar/Ate1^tm2.1Avar Tg(Prnp-cre/ERT)28.8Ics/0	involves: 129S1/Sv * C57BL/6 * CBA * SJL	MGI:4415720

Allelic Composition	Ate1^tm1Avar/Ate1^tm2.1Avar Tg(Prnp-cre/ERT)28.8Ics/0
Genetic Background	involves: 129S1/Sv * C57BL/6 * CBA * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ate1^tm1Avar mutation (0 available); any Ate1 mutation (43 available)
Ate1^tm2.1Avar mutation (0 available); any Ate1 mutation (43 available)
Tg(Prnp-cre/ERT)28.8Ics mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reduced male fertility ( J:155421 )

• 33% fewer litters and 50% fewer pups are produced

• matings start from1 month following tamoxifen treatment

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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