Analysis Tools
growth/size/body
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• females show increased lean mass after low and high fat feeding compared to controls
• however, on a moderate fat breeder diet no differences in lean body mass are detected
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• on both low and high fat diets, males gain less weight than controls, whereas females gain significantly more weight compared to controls on both diets
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• in males, overall body weight is significantly decreased
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immune system
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• Il-15 protein levels are higher in muscle relative to controls; females display higher levels than males
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• protein levels are higher than in controls; females have higher levels than males
• circulating levels of other cytokines are not affected by genotype
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homeostasis/metabolism
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• males, but not females, have significantly lower fasting serum leptin levels compared to controls
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• Il-15 protein levels are higher in muscle relative to controls; females display higher levels than males
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• protein levels are higher than in controls; females have higher levels than males
• circulating levels of other cytokines are not affected by genotype
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adipose tissue
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• mean visceral fat cell cross-sectional area in males is about 50% of that of controls, but is not different in females
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• significantly reduced in males and females relative to controls
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skeleton
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• bone mineral content is significantly higher relative to controls, with males show an 8% elevation and females a 24% elevation in bone mineral content
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hematopoietic system
| N |
• no splenic enlargement or increased cellularity of the spleen or blood is detected
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muscle
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• wet weight of fast-twitch muscle is significantly lower in males, but not in females
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limbs/digits/tail
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• wet weight of fast-twitch muscle is significantly lower in males, but not in females
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