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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ntsr1tm1Pang
targeted mutation 1, Zhen Pang
MGI:4418203
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ntsr1tm1Pang/Ntsr1tm1Pang C57BL/6-Ntsr1tm1Pang MGI:4418207


Genotype
MGI:4418207
hm1
Allelic
Composition		 Ntsr1tm1Pang/Ntsr1tm1Pang
Genetic
Background		 C57BL/6-Ntsr1tm1Pang
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ntsr1tm1Pang mutation (0 available); any Ntsr1 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal startle reflex ( J:155775 )
• unaffected by treatment with PD149163 in contrast to decreased responses in controls
decreased startle reflex ( J:155775 )
• males treated with amphetamine have reduced startle responses whereas females show no affect
• startle responses are lower in both sexes after treatment with dizocilpine except at the highest doses

nervous system
abnormal prepulse inhibition ( J:155775 )
• unaffected by PD149163 in contrast to controls which display increased prepulse inhibition




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory