All Phenotypes Pdcd4<tm1.1Tosc> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pdcd4^tm1.1Tosc
targeted mutation 1.1, Tobias Schmid
MGI:4418524

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pdcd4^tm1.1Tosc/Pdcd4^tm1.1Tosc	involves: 129 * C57BL/6 * CD-1	MGI:4418556

Allelic Composition	Pdcd4^tm1.1Tosc/Pdcd4^tm1.1Tosc
Genetic Background	involves: 129 * C57BL/6 * CD-1

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdcd4^tm1.1Tosc mutation (0 available); any Pdcd4 mutation (21 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased papilloma incidence ( J:132696 )

• increase from 2.91 tumors/control mouse to 5.11 tumors/mutant null mouse

• papilloma incidence increases from 46% in control mice to 84% in mutant mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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