Phenotypes associated with this allele

• Allele Symbol: Aars2^{tm1(KOMP)Wtsi}
• Allele Name: targeted mutation 1, Wellcome Trust Sanger Institute
• Allele ID: MGI:4419134
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Aars2^tm1(KOMP)Wtsi/Aars2^tm1(KOMP)Wtsi	C57BL/6N-Aars2^tm1(KOMP)Wtsi/Nju	MGI:5767551
ht2	Aars2^tm1(KOMP)Wtsi/Aars2^+	C57BL/6N-Aars2^tm1(KOMP)Wtsi/Nju	MGI:5756631

Genotype
MGI:5767551

hm1

• Allelic Composition: Aars2^{tm1(KOMP)Wtsi}/Aars2^{tm1(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Aars2^{tm1(KOMP)Wtsi}/Nju
• Cell Lines: EPD0406_3_A04

Data Sources

IMPC Data for Aars2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - MARC

Genotype
MGI:5756631

ht2

• Allelic Composition: Aars2^{tm1(KOMP)Wtsi}/Aars2⁺
• Genetic Background: C57BL/6N-Aars2^{tm1(KOMP)Wtsi}/Nju
• Cell Lines: EPD0406_3_A04

Data Sources

IMPC Data for Aars2

behavior/neurological

impaired pupillary reflex ( J:211773 )

♀

IMPC - MARC

abnormal vocalization ( J:211773 )

IMPC - MARC

cardiovascular system

abnormal heart left ventricle morphology ( J:211773 )

♀

IMPC - MARC

hematopoietic system

increased basophil cell number ( J:211773 )

♂

IMPC - MARC

increased eosinophil cell number ( J:211773 )

♂

IMPC - MARC

decreased red blood cell distribution width ( J:211773 )

♂

IMPC - MARC

increased neutrophil cell number ( J:211773 )

IMPC - MARC

immune system

increased basophil cell number ( J:211773 )

♂

IMPC - MARC

increased eosinophil cell number ( J:211773 )

♂

IMPC - MARC

increased neutrophil cell number ( J:211773 )

IMPC - MARC

vision/eye

impaired pupillary reflex ( J:211773 )

♀

IMPC - MARC