About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhot2tm1(KOMP)Wtsi
targeted mutation 1, Wellcome Trust Sanger Institute
MGI:4419477
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rhot2tm1(KOMP)Wtsi/Rhot2tm1(KOMP)Wtsi C57BL/6N-Rhot2tm1(KOMP)Wtsi/Wtsi MGI:5781723
hm2
 		Rhot2tm1(KOMP)Wtsi/Rhot2tm1(KOMP)Wtsi involves: C57BL/6N * C57BL/6NTac MGI:5906218


Genotype
MGI:5781723
hm1
Allelic
Composition		 Rhot2tm1(KOMP)Wtsi/Rhot2tm1(KOMP)Wtsi
Genetic
Background		 C57BL/6N-Rhot2tm1(KOMP)Wtsi/Wtsi
Cell Lines EPD0389_5_A05
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhot2tm1(KOMP)Wtsi mutation (3 available); any Rhot2 mutation (28 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased lean body mass ( J:175295 )
IMPC - WTSI
decreased body weight ( J:175295 )
IMPC - WTSI

homeostasis/metabolism

skeleton




Genotype
MGI:5906218
hm2
Allelic
Composition		 Rhot2tm1(KOMP)Wtsi/Rhot2tm1(KOMP)Wtsi
Genetic
Background		 involves: C57BL/6N * C57BL/6NTac
Cell Lines EPD0389_5_A05
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhot2tm1(KOMP)Wtsi mutation (3 available); any Rhot2 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:240500 )
• mice are viable and fertile and exhibit normal mitochondria trafficking in neurons as well as normal neuron morphology




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory