Phenotypes associated with this allele

• Allele Symbol: Xpnpep1^{tm1a(KOMP)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4419636
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Xpnpep1^tm1a(KOMP)Wtsi/Xpnpep1^tm1a(KOMP)Wtsi	C57BL/6N-Xpnpep1^tm1a(KOMP)Wtsi/Wtsi	MGI:5631693

Genotype
MGI:5631693

hm1

• Allelic Composition: Xpnpep1^{tm1a(KOMP)Wtsi}/Xpnpep1^{tm1a(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Xpnpep1^{tm1a(KOMP)Wtsi}/Wtsi
• Cell Lines: EPD0383_7_C09

Data Sources

IMPC Data for Xpnpep1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal vertebral artery topology ( J:239583 )

DMDD

dilated liver sinusoidal space ( J:239583 )

DMDD

abnormal umbilical vein topology ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal inferior vena cava morphology ( J:239583 )

DMDD

abnormal superior vena cava morphology ( J:239583 )

DMDD

abnormal mitral valve morphology ( J:239583 )

DMDD

abnormal inferior vena cava valve morphology ( J:239583 )

DMDD

muscular ventricular septal defect ( J:239583 )

DMDD

abnormal aortic valve morphology ( J:239583 )

DMDD

craniofacial

abnormal cranium morphology ( J:211773 )

♂

IMPC - WTSI

digestive/alimentary system

abnormal intestine placement ( J:239583 )

DMDD

embryo

abnormal umbilical vein topology ( J:239583 )

DMDD

abnormal vitelline vein topology ( J:239583 )

DMDD

abnormal Mullerian duct morphology ( J:239583 )

DMDD

endocrine/exocrine glands

abnormal bile duct morphology ( J:239583 )

DMDD

abnormal thymus morphology ( J:239583 )

DMDD

hematopoietic system

abnormal thymus morphology ( J:239583 )

DMDD

increased NK cell number ( J:211773 )

IMPC - WTSI

increased gamma-delta T cell number ( J:211773 )

♂

IMPC - WTSI

homeostasis/metabolism

subcutaneous edema ( J:239583 )

DMDD

immune system

abnormal thymus morphology ( J:239583 )

DMDD

increased NK cell number ( J:211773 )

IMPC - WTSI

increased gamma-delta T cell number ( J:211773 )

♂

IMPC - WTSI

blood in lymph vessels ( J:239583 )

DMDD

integument

subcutaneous edema ( J:239583 )

DMDD

liver/biliary system

dilated liver sinusoidal space ( J:239583 )

DMDD

abnormal bile duct morphology ( J:239583 )

DMDD

mortality/aging

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - WTSI

muscle

abnormal eye muscle morphology ( J:239583 )

DMDD

abnormal infrahyoid muscle morphology ( J:239583 )

DMDD

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

neoplasm

increased hemangioma incidence ( J:239583 )

DMDD

increased trigeminal neuroma incidence ( J:239583 )

DMDD

embryo tumor ( J:239583 )

DMDD

nervous system

increased trigeminal neuroma incidence ( J:239583 )

DMDD

abnormal hypoglossal nerve topology ( J:239583 )

DMDD

respiratory system

abnormal infrahyoid muscle morphology ( J:239583 )

DMDD

abnormal infrahyoid muscle connection ( J:239583 )

DMDD

skeleton

abnormal cranium morphology ( J:211773 )

♂

IMPC - WTSI

vision/eye

abnormal eye muscle morphology ( J:239583 )

DMDD