mortality/aging
• all mice die prior to E9.5
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• few mice are present at E8.5
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embryo
• no defined internal structures at E7.5 with lack of organized mesoderm and ectoderm layers, allantois, amnion, chorion, and embryonic structures
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• developmentally arrested or even degenerating at E7.5
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• at E7.5
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• at E7.5
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• at E7.5
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growth/size/body
• developmentally arrested or even degenerating at E7.5
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