mortality/aging
• survival is improved compared to null mice not carrying the transgene but still less than that of wild-type controls
• relative viability compared to wild-type controls is 68%
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skeleton
• many mice have extra pair of true ribs
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• many mice have extra rib-bearing thoracic vertebrae
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• many mice are missing a lumbar vertebra
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• many mice have extra rib-bearing thoracic vertebra indicating homeotic transformation
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reproductive system