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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Lfng-LFNG)2Dihz
transgene insertion 2, David Ish-Horowicz
MGI:4420241
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Lfngtm1Rjo/Lfngtm1Rjo
Tg(Lfng-LFNG)2Dihz/?
involves: 129S7/SvEvBrd * C57BL/6J * CBA MGI:4420256


Genotype
MGI:4420256
cx1
Allelic
Composition
Lfngtm1Rjo/Lfngtm1Rjo
Tg(Lfng-LFNG)2Dihz/?
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lfngtm1Rjo mutation (0 available); any Lfng mutation (32 available)
Tg(Lfng-LFNG)2Dihz mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Adult tail phenotype of Lfngtm1Rjo/Lfngtm1Rjo and Hes7tm1.1Dihz/Hes7tm1.1Dihz mice and the effect on the Lfng tail phenotype by transgenic expression in the stripe domain

mortality/aging
• survival is improved compared to null mice not carrying the transgene but still less than that of wild-type controls
• relative viability compared to wild-type controls is 68%

skeleton
• many mice have extra pair of true ribs
• many mice have extra rib-bearing thoracic vertebrae
• many mice are missing a lumbar vertebra
• many mice have extra rib-bearing thoracic vertebra indicating homeotic transformation

reproductive system





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory