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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Eno2-Pomc)1Mobb
transgene insertion 1, Charles V Mobbs
MGI:4420545
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Lepob/Lepob
Tg(Eno2-Pomc)1Mobb/?
involves: C3H * C57BL/6 MGI:4429455


Genotype
MGI:4429455
cx1
Allelic
Composition
Lepob/Lepob
Tg(Eno2-Pomc)1Mobb/?
Genetic
Background
involves: C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lepob mutation (5 available); any Lep mutation (21 available)
Tg(Eno2-Pomc)1Mobb mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• body size is significantly reduced relative to Lepob mice but still larger than wild-type controls
• body weight is significantly reduced relative to Lepob mice but still heavier than wild-type controls

liver/biliary system
• partially corrected relative to Lepob

homeostasis/metabolism
N
• normalized glucose levels in urine
• normalized glucose tolerance
• normalized serum insulin levels
• normalized insulin sensitivity
• partial reversal of reduced body temperature seen in Lepob mice
• partially corrected relative to Lepob

behavior/neurological
• moderated relative to Lepob





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory