growth/size/body
• body size is significantly reduced relative to Lepob mice but still larger than wild-type controls
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• body weight is significantly reduced relative to Lepob mice but still heavier than wild-type controls
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liver/biliary system
• partially corrected relative to Lepob
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homeostasis/metabolism
N |
• normalized glucose levels in urine
• normalized glucose tolerance
• normalized serum insulin levels
• normalized insulin sensitivity
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• partial reversal of reduced body temperature seen in Lepob mice
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• partially corrected relative to Lepob
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behavior/neurological
• moderated relative to Lepob
|