Phenotypes associated with this allele

• Allele Symbol: Slc20a1^tm1.2Cmg
• Allele Name: targeted mutation 1.2, Cecilia M Giachelli
• Allele ID: MGI:4421036
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Slc20a1^tm1.2Cmg/Slc20a1^tm1.2Cmg	involves: 129S6/SvEvTac * C57BL/6 * CBA * DBA/2 * SJL	MGI:4421044

Genotype
MGI:4421044

hm1

• Allelic Composition: Slc20a1^tm1.2Cmg/Slc20a1^tm1.2Cmg
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * DBA/2 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Slc20a1^tm1.2Cmg/Slc20a1^tm1.2Cmg embryos are developmentally delayed and anemic and yolk sacs lack mature vasculature

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:156027 )

• embryos are resorbed between E12.5 and E14.5

embryo

abnormal vitelline vasculature morphology ( J:156027 )

• at E10.5, some mice exhibit an absence of superficial yolk sac vasculature unlike in wild-type mice

• at E12.5, all mice exhibit abnormal yolk vasculature compared with wild-type mice

embryonic growth retardation ( J:156027 )

• at E12.5

hematopoietic system

anemia ( J:156027 )

• some mice at E10.5 and all mice at E12.5

growth/size/body

embryonic growth retardation ( J:156027 )

• at E12.5

cardiovascular system

abnormal vitelline vasculature morphology ( J:156027 )

• at E10.5, some mice exhibit an absence of superficial yolk sac vasculature unlike in wild-type mice

• at E12.5, all mice exhibit abnormal yolk vasculature compared with wild-type mice