Phenotypes associated with this allele

• Allele Symbol: Otog^twt-4J
• Allele Name: twister 4 Jackson
• Allele ID: MGI:4421285
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Otog^twt-4J/Otog^twt-4J	C57BL/6J-Otog^twt-4J/Kjn	MGI:4421396

Genotype
MGI:4421396

hm1

• Allelic Composition: Otog^twt-4J/Otog^twt-4J
• Genetic Background: C57BL/6J-Otog^twt-4J/Kjn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal otolith morphology ( J:156739 )

• whole mounts of inner ears show otoconial deficiencies that are likely due to displacement of the otolithic membrane

increased or absent threshold for auditory brainstem response ( J:156739 )

• at wean age homozygotes have severe hearing impairment as assessed by auditory-evoked brainstem response and are deaf by 70 days of age

deafness ( J:156739 )

• profoundly deaf by 70 days of age

behavior/neurological

impaired swimming ( J:156739 )

• homozygotes swim tilted to one side in circles usually just below the surface of the water

head tilt ( J:156739 )

• severe