Phenotypes associated with this allele

• Allele Symbol: Trpm1^tm1Tfur
• Allele Name: targeted mutation 1, Takahisa Furukawa
• Allele ID: MGI:4421441
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trpm1^tm1Tfur/Trpm1^tm1Tfur	involves: 129S6/SvEvTac	MGI:4421442

Genotype
MGI:4421442

hm1

• Allelic Composition: Trpm1^tm1Tfur/Trpm1^tm1Tfur
• Genetic Background: involves: 129S6/SvEvTac

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal cone electrophysiology ( J:156502 )

• membrane current fluctuations of ON bipolar cells in the dark are much smaller than in wild-type mice

• significant difference in the amplitude of photoresponses compared to wild-type

• light stimulation fails to induce an inward current in cone ON bipolar cells

• in contrast no abnormalities are detected in the response of cone OFF bipolar cells

abnormal rod electrophysiology ( J:156502 )

• light stimulation fails to induce an inward current in rod bipolar cells

• significant difference in the amplitude of photoresponses compared to wild-type