Analysis Tools
reproductive system
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• increase in apoptosis of germ cells, mainly haploid round spermatids, at P17 and P30
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• sperm are immotile
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• mature elongated spermatids and spermatozoa are absent unlike in wild-type mice
• overall the spermatogenic process is delayed
• however, early stages of spermatogenesis are normal
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• the number of spermatozoa is reduced to 10% of wild-type
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• the few produced sperm have awkward shapes and broken tails unlike in wild-type mice
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• the few produced sperm have broken tails unlike in wild-type mice
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• the few produced sperm have broken tails unlike in wild-type mice
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cellular
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• the number of spermatozoa is reduced to 10% of wild-type
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• the few produced sperm have awkward shapes and broken tails unlike in wild-type mice
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• the few produced sperm have broken tails unlike in wild-type mice
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|
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• increase in apoptosis of germ cells, mainly haploid round spermatids, at P17 and P30
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|
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• sperm are immotile
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