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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pgk2tm1Dao
targeted mutation 1, Deborah A O'Brien
MGI:4421784
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pgk2tm1Dao/Pgk2tm1Dao involves: 129S6/SvEvTac * C57BL/6NCrl MGI:4421786


Genotype
MGI:4421786
hm1
Allelic
Composition		 Pgk2tm1Dao/Pgk2tm1Dao
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pgk2tm1Dao mutation (2 available); any Pgk2 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:156646 )
N
• mice exhibit normal testis histology, sperm counts, and sperm ultrastructure
decreased sperm progressive motility ( J:156646 )
• progressive motility is impaired
asthenozoospermia ( J:156646 )
• progressiveness and other quantitative parameters of sperm motility are reduced
male infertility ( J:156646 )
• some mice

cellular
decreased sperm progressive motility ( J:156646 )
• progressive motility is impaired
asthenozoospermia ( J:156646 )
• progressiveness and other quantitative parameters of sperm motility are reduced




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory