About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kdrtm1.1Eia
targeted mutation 1.1, Anne Eichmann
MGI:4429911
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kdrtm1.1Eia/Kdrtm1.1Eia B6.129P2-Kdrtm1.1Eia MGI:4429913
cx2
 		Kdrtm1.1Eia/Kdr+
Nrp2tm1Ddg/Nrp2+ 		involves: 129P2/OlaHsd * C57BL/6 MGI:4429919


Genotype
MGI:4429913
hm1
Allelic
Composition		 Kdrtm1.1Eia/Kdrtm1.1Eia
Genetic
Background		 B6.129P2-Kdrtm1.1Eia
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm1.1Eia mutation (0 available); any Kdr mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:156869 )
• homozygous mice die at early embryonic stages

cardiovascular system
abnormal vascular development ( J:156869 )
• failure of blood vessel formation




Genotype
MGI:4429919
cx2
Allelic
Composition		 Kdrtm1.1Eia/Kdr+
Nrp2tm1Ddg/Nrp2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdrtm1.1Eia mutation (0 available); any Kdr mutation (74 available)
Nrp2tm1Ddg mutation (0 available); any Nrp2 mutation (89 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:156869 )
N
• no obvious alteration in capillary density or patterning
• normal lymphatic vessel patterning and sprouting




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory