Phenotypes associated with this allele

• Allele Symbol: Zfp24^tm1Jifu
• Allele Name: targeted mutation 1, Jiliang Fu
• Allele ID: MGI:4430080
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Zfp24^tm1Jifu/Zfp24^tm1Jifu	involves: 129X1/SvJ * C57BL/6J	MGI:4430081

Genotype
MGI:4430081

hm1

• Allelic Composition: Zfp24^tm1Jifu/Zfp24^tm1Jifu
• Genetic Background: involves: 129X1/SvJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:156988 )

• embryonic death at around 7.5 days post-coitum due to impaired cell proliferation

embryo

absent inner cell mass proliferation ( J:156988 )

• by day 3 of culturing of E3.5 blastocysts, the ICM has stopped proliferating

inner cell mass degeneration ( J:156988 )

• by day 3 of culturing of E3.5 blastocysts the ICM has stopped proliferating, and they degenerate soon after

abnormal extraembryonic tissue physiology ( J:156988 )

• trophoblastic giant cells fail to proliferate but persist in culture for 7 days

cellular

absent inner cell mass proliferation ( J:156988 )

• by day 3 of culturing of E3.5 blastocysts, the ICM has stopped proliferating