Phenotypes associated with this allele

• Allele Symbol: Pax6^Sey-4H
• Allele Name: small-eye, Harwell 4
• Allele ID: MGI:4430205
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Pax6^Sey-4H/Pax6^+	involves: 101/H * C3H/HeCrj * C3H/HeH	MGI:4430208

Genotype
MGI:4430208

ht1

• Allelic Composition: Pax6^Sey-4H/Pax6⁺
• Genetic Background: involves: 101/H * C3H/HeCrj * C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:124276 )

• shorter life span

neoplasm

increased tumor incidence ( J:124276 )

• latency of tumor formation decreased by radiation exposure

increased alimentary system tumor incidence ( J:124276 )

• increased tumor incidence in the alimentary tract regardless of irradiation

increased intestinal adenoma incidence ( J:124276 )

• tubular adenomas and adenocarcinomas form at the junction between the pylorus and the duodenum or the posterior ileum

increased stomach tumor incidence ( J:124276 )

• squamous cell carcinomas form in the forestomach

endocrine/exocrine glands

increased susceptibility to induced pancreatitis ( J:124276 )

• develop acute or chronic pancreatitis when exposed to radiation

immune system

increased susceptibility to induced pancreatitis ( J:124276 )

• develop acute or chronic pancreatitis when exposed to radiation

digestive/alimentary system

increased alimentary system tumor incidence ( J:124276 )

• increased tumor incidence in the alimentary tract regardless of irradiation

increased intestinal adenoma incidence ( J:124276 )

• tubular adenomas and adenocarcinomas form at the junction between the pylorus and the duodenum or the posterior ileum

increased stomach tumor incidence ( J:124276 )

• squamous cell carcinomas form in the forestomach