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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Mt1-rPRL)Jto
transgene insertion, Jan Tornell
MGI:4430625
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Mt1-rPRL)Jto/0 involves: C57BL/6J * CBA MGI:4430628


Genotype
MGI:4430628
tg1
Allelic
Composition
Tg(Mt1-rPRL)Jto/0
Genetic
Background
involves: C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• female mice exhibit a 130% increase in lacrimal gland acini per field compared to in wild-type mice due to a decline in average acinar area associated with an increase in acinar cells per field
• however, the lacrimal gland in male mice is normal
• female mice exhibit a 10% increase in acinar cell density compared with wild-type mice
• however, the Harderian gland in male mice is normal
• male and female mice exhibit an increase in solid porphyrin accretions compared with wild-type mice

vision/eye
• female mice exhibit a 130% increase in lacrimal gland acini per field compared to in wild-type mice due to a decline in average acinar area associated with an increase in acinar cells per field
• however, the lacrimal gland in male mice is normal





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory