Phenotypes associated with this allele

• Allele Symbol: Tg(Mt1-rPRL)Jto
• Allele Name: transgene insertion, Jan Tornell
• Allele ID: MGI:4430625
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Mt1-rPRL)Jto/0	involves: C57BL/6J * CBA	MGI:4430628

Genotype
MGI:4430628

tg1

• Allelic Composition: Tg(Mt1-rPRL)Jto/0
• Genetic Background: involves: C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal lacrimal gland morphology ( J:66544 )

• female mice exhibit a 130% increase in lacrimal gland acini per field compared to in wild-type mice due to a decline in average acinar area associated with an increase in acinar cells per field

• however, the lacrimal gland in male mice is normal

abnormal Harderian gland morphology ( J:66544 )

• female mice exhibit a 10% increase in acinar cell density compared with wild-type mice

• however, the Harderian gland in male mice is normal

abnormal Harderian gland porphyrin secretion ( J:66544 )

• male and female mice exhibit an increase in solid porphyrin accretions compared with wild-type mice

vision/eye

abnormal lacrimal gland morphology ( J:66544 )

• female mice exhibit a 130% increase in lacrimal gland acini per field compared to in wild-type mice due to a decline in average acinar area associated with an increase in acinar cells per field

• however, the lacrimal gland in male mice is normal