endocrine/exocrine glands
• female mice exhibit a 130% increase in lacrimal gland acini per field compared to in wild-type mice due to a decline in average acinar area associated with an increase in acinar cells per field
• however, the lacrimal gland in male mice is normal
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• female mice exhibit a 10% increase in acinar cell density compared with wild-type mice
• however, the Harderian gland in male mice is normal
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• male and female mice exhibit an increase in solid porphyrin accretions compared with wild-type mice
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vision/eye
• female mice exhibit a 130% increase in lacrimal gland acini per field compared to in wild-type mice due to a decline in average acinar area associated with an increase in acinar cells per field
• however, the lacrimal gland in male mice is normal
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