Analysis Tools
homeostasis/metabolism
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• when fed a high fat diet
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• in a hyperinsulinemic-euglycemic clamp study, peripheral glucose disposal is diminished compared to in wild-type mice
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• when mice are fed standard chow or fasted
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• when mice are fed standard chow or fasted
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• in a glucose tolerance test, glucose excursion is greater than in wild-type mice
• when fed a high fat diet, mice exhibit greater glucose intolerance compared with similarly treated wild-type mice
• however, inhibition of fatty acid oxidation improves glucose tolerance
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• when fed a high fat or standard diet
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• increased within skeletal muscle when mice are fed a high fat diet
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adipose tissue
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• when fed a high fat diet
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• when fed a high fat diet
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growth/size/body
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• when fed a high fat diet
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muscle
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• basal and insulin-stimulated glucose uptake is reduced compared to in wild-type mice
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• increased within skeletal muscle when mice are fed a high fat diet
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integument
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• when fed a high fat diet
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cellular
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• basal and insulin-stimulated glucose uptake is reduced compared to in wild-type mice
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