endocrine/exocrine glands
• cerulein-treated mice fail to exhibit pancreas acinar cell loss and necrosis unlike similarly treated wild-type mice
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cellular
• Trail plus Smac-, TNF-a/Smac mimetic/z-VAD-, or TRAIL/Smac mimetic/z-VAD-treated mouse embryonic fibroblasts (MEFs) fail to undergo cell death (apoptosis or necrosis) unlike similarly treated wild-type mice
• however, MEFs undergo apoptosis following treatment with TNF-a plus cycloheximide
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