Phenotypes associated with this allele

• Allele Symbol: Plppr4^tm2.1Roni
• Allele Name: targeted mutation 2.1, Robert Nitsch
• Allele ID: MGI:4431224
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Plppr4^tm2.1Roni/Plppr4^tm2.1Roni	involves: 129P2/OlaHsd * C57BL/6	MGI:4431243

Genotype
MGI:4431243

cn1

• Allelic Composition: Plppr4^tm2.1Roni/Plppr4^tm2.1Roni
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:157318 )

N • at P21, mice do not exhibit seizures

increased excitatory postsynaptic current amplitude ( J:157318 )

• at P20, CA1 neurons electroporated with a cre recombinase construct in utero exhibit an increase in stimulus-evoked excitatory postsynaptic current amplitudes compared wild-type cells

increased miniature excitatory postsynaptic current frequency ( J:157318 )

• CA1 neurons electroporated with a cre recombinase construct in utero exhibit an increase in miniature excitatory postsynaptic current frequency compared with wild-type cells

behavior/neurological

behavior/neurological phenotype ( J:157318 )

N • at P21, mice do not exhibit seizures