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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Pitpnm1tm1a(EUCOMM)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4431584
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Pitpnm1tm1a(EUCOMM)Wtsi/Pitpnm1tm1a(EUCOMM)Wtsi C57BL/6N-Pitpnm1tm1a(EUCOMM)Wtsi/Wtsi MGI:5781698
hm2
Pitpnm1tm1a(EUCOMM)Wtsi/Pitpnm1tm1a(EUCOMM)Wtsi involves: C57BL/6N MGI:5555030


Genotype
MGI:5781698
hm1
Allelic
Composition
Pitpnm1tm1a(EUCOMM)Wtsi/Pitpnm1tm1a(EUCOMM)Wtsi
Genetic
Background
C57BL/6N-Pitpnm1tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0425_4_A09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pitpnm1tm1a(EUCOMM)Wtsi mutation (2 available); any Pitpnm1 mutation (53 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system

homeostasis/metabolism




Genotype
MGI:5555030
hm2
Allelic
Composition
Pitpnm1tm1a(EUCOMM)Wtsi/Pitpnm1tm1a(EUCOMM)Wtsi
Genetic
Background
involves: C57BL/6N
Cell Lines EPD0425_4_A09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pitpnm1tm1a(EUCOMM)Wtsi mutation (2 available); any Pitpnm1 mutation (53 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in male, but not female, mice fed a high fat diet
• in male, but not female, mice fed a high fat diet

hearing/vestibular/ear
N
• mice exhibit no hearing defect
• slight at 14 weeks at 6 kHz, but not sufficient to be biologically meaningful
• however, ABR thresholds are normal at 7 weeks

immune system
• in female, but not male, mice fed a high fat diet

vision/eye
N
• mice exhibit normal eyes

hematopoietic system
• in female, but not male, mice fed a high fat diet





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory