Phenotypes associated with this allele

• Allele Symbol: Parvb^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4431642
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Parvb^tm1a(EUCOMM)Wtsi/Parvb^tm1a(EUCOMM)Wtsi	C57BL/6N-Parvb^tm1a(EUCOMM)Wtsi/Cnrm	MGI:5782156

Genotype
MGI:5782156

hm1

• Allelic Composition: Parvb^{tm1a(EUCOMM)Wtsi}/Parvb^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Parvb^{tm1a(EUCOMM)Wtsi}/Cnrm
• Cell Lines: EPD0087_5_C08

Data Sources

IMPC Data for Parvb

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body weight ( J:165965 )

♀

IMPC - HAR

increased body weight ( J:165965 )

♂

IMPC - HAR

hematopoietic system

decreased mature B cell number ( J:165965 )

IMPC - HAR

decreased NK cell number ( J:165965 )

♂

IMPC - HAR

decreased T cell number ( J:165965 )

IMPC - HAR

homeostasis/metabolism

decreased circulating glucose level ( J:165965 )

♂

IMPC - HAR

decreased circulating cholesterol level ( J:165965 )

♂

IMPC - HAR

decreased circulating iron level ( J:165965 )

IMPC - HAR

decreased circulating total protein level ( J:165965 )

♂

IMPC - HAR

immune system

decreased mature B cell number ( J:165965 )

IMPC - HAR

decreased NK cell number ( J:165965 )

♂

IMPC - HAR

decreased T cell number ( J:165965 )

IMPC - HAR

skeleton

decreased bone mineral density ( J:165965 )

♀

IMPC - HAR

increased bone mineral density ( J:165965 )

♂

IMPC - HAR

abnormal bone mineralization ( J:165965 )

IMPC - HAR