Phenotypes associated with this allele

• Allele Symbol: Mtor^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4432158
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mtor^tm1a(EUCOMM)Wtsi/Mtor^tm1a(EUCOMM)Wtsi	C57BL/6N-Mtor^tm1a(EUCOMM)Wtsi/Wtsi	MGI:6262942
ht2	Mtor^tm1a(EUCOMM)Wtsi/Mtor^+	C57BL/6N-Mtor^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5781675

Genotype
MGI:6262942

hm1

• Allelic Composition: Mtor^{tm1a(EUCOMM)Wtsi}/Mtor^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Mtor^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0046_3_B11

Data Sources

IMPC Data for Mtor

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - WTSI

Genotype
MGI:5781675

ht2

• Allelic Composition: Mtor^{tm1a(EUCOMM)Wtsi}/Mtor⁺
• Genetic Background: C57BL/6N-Mtor^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0046_3_B11

Data Sources

IMPC Data for Mtor

hematopoietic system

increased mean corpuscular hemoglobin ( J:175295 )

IMPC - WTSI

homeostasis/metabolism

decreased blood urea nitrogen level ( J:175295 )

IMPC - WTSI

decreased circulating LDL cholesterol level ( J:175295 )

♂

IMPC - WTSI

increased circulating LDL cholesterol level ( J:175295 )

♀

IMPC - WTSI