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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dynlrb1tm1a(EUCOMM)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4432163
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1tm1a(EUCOMM)Wtsi C57BL/6N-Dynlrb1tm1a(EUCOMM)Wtsi/Wtsi MGI:5631080
hm2
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1tm1a(EUCOMM)Wtsi involves: C57BL/6N MGI:6466699
ht3
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1+ C57BL/6N-Dynlrb1tm1a(EUCOMM)Wtsi/Wtsi MGI:6461227
ht4
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1+ involves: C57BL/6N MGI:6466701
cx5
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1+
Tg(Thy1-YFP)16Jrs/0
involves: C57BL/6J * C57BL/6N MGI:6466700


Genotype
MGI:5631080
hm1
Allelic
Composition
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1tm1a(EUCOMM)Wtsi
Genetic
Background
C57BL/6N-Dynlrb1tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0373_7_C01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dynlrb1tm1a(EUCOMM)Wtsi mutation (1 available); any Dynlrb1 mutation (13 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging




Genotype
MGI:6466699
hm2
Allelic
Composition
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1tm1a(EUCOMM)Wtsi
Genetic
Background
involves: C57BL/6N
Cell Lines EPD0373_7_C01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dynlrb1tm1a(EUCOMM)Wtsi mutation (1 available); any Dynlrb1 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygous mutant embryos die before E9.5




Genotype
MGI:6461227
ht3
Allelic
Composition
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1+
Genetic
Background
C57BL/6N-Dynlrb1tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0373_7_C01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dynlrb1tm1a(EUCOMM)Wtsi mutation (1 available); any Dynlrb1 mutation (13 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton




Genotype
MGI:6466701
ht4
Allelic
Composition
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1+
Genetic
Background
involves: C57BL/6N
Cell Lines EPD0373_7_C01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dynlrb1tm1a(EUCOMM)Wtsi mutation (1 available); any Dynlrb1 mutation (13 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• dorsal root ganglia (DRG) neurons show reduced beta-catenin nuclear accumulation after 48 h in culture




Genotype
MGI:6466700
cx5
Allelic
Composition
Dynlrb1tm1a(EUCOMM)Wtsi/Dynlrb1+
Tg(Thy1-YFP)16Jrs/0
Genetic
Background
involves: C57BL/6J * C57BL/6N
Cell Lines EPD0373_7_C01
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dynlrb1tm1a(EUCOMM)Wtsi mutation (1 available); any Dynlrb1 mutation (13 available)
Tg(Thy1-YFP)16Jrs mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• DRG neurons exhibit significantly reduced axon outgrowth after 48 h in culture

cellular
• DRG neurons exhibit significantly reduced axon outgrowth after 48 h in culture





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory