All Phenotypes Cep152<tm1a(EUCOMM)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Cep152^{tm1a(EUCOMM)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4432204

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cep152^{tm1a(EUCOMM)Wtsi}/Cep152^{tm1a(EUCOMM)Wtsi}	involves: C57BL/6N * FVB/NJ	MGI:5609814

Allelic Composition	Cep152^{tm1a(EUCOMM)Wtsi}/Cep152^{tm1a(EUCOMM)Wtsi}
Genetic Background	involves: C57BL/6N * FVB/NJ
Cell Lines	EPD0061_1_E05

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cep152^{tm1a(EUCOMM)Wtsi} mutation (0 available); any Cep152 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal embryonic neuroepithelium morphology ( J:208632 )

• decrease in the number of centrosomes and cilia

decreased embryonic neuroepithelium primary cilium number ( J:208632 )

nervous system

abnormal embryonic neuroepithelium morphology ( J:208632 )

• decrease in the number of centrosomes and cilia

decreased embryonic neuroepithelium primary cilium number ( J:208632 )

cellular

decreased embryonic neuroepithelium primary cilium number ( J:208632 )

abnormal centrosome morphology ( J:208632 )

• decrease in the number of centrosomes in embryonic neural epithelium

increased apoptosis ( J:208632 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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