Phenotypes associated with this allele

• Allele Symbol: Xbp1^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4432347
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Xbp1^tm1a(EUCOMM)Wtsi/Xbp1^+	C57BL/6N-Xbp1^tm1a(EUCOMM)Wtsi/Ics	MGI:5782227

Genotype
MGI:5782227

ht1

• Allelic Composition: Xbp1^{tm1a(EUCOMM)Wtsi}/Xbp1⁺
• Genetic Background: C57BL/6N-Xbp1^{tm1a(EUCOMM)Wtsi}/Ics
• Cell Lines: EPD0038_2_B10

Data Sources

IMPC Data for Xbp1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased grip strength ( J:165965 )

IMPC - HMGU

hematopoietic system

decreased T cell number ( J:165965 )

♂

IMPC - HMGU

decreased IgG1 level ( J:165965 )

♂

IMPC - HMGU

homeostasis/metabolism

decreased circulating cholesterol level ( J:165965 )

♂

IMPC - HMGU

decreased circulating triglyceride level ( J:165965 )

IMPC - HMGU

immune system

decreased T cell number ( J:165965 )

♂

IMPC - HMGU

decreased IgG1 level ( J:165965 )

♂

IMPC - HMGU

skeleton

vertebral fusion ( J:165965 )

IMPC - ICS

abnormal bone structure ( J:165965 )

IMPC - HMGU

abnormal bone mineralization ( J:165965 )

IMPC - HMGU