Phenotypes associated with this allele

• Allele Symbol: Bbx^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4432372
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Bbx^tm1a(EUCOMM)Wtsi/Bbx^tm1a(EUCOMM)Wtsi	B6JTyr;B6N-Bbx^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5781580
hm2	Bbx^tm1a(EUCOMM)Wtsi/Bbx^tm1a(EUCOMM)Wtsi	involves: C57BL/6 * C57BL/6N	MGI:5790947

Genotype
MGI:5781580

hm1

• Allelic Composition: Bbx^{tm1a(EUCOMM)Wtsi}/Bbx^{tm1a(EUCOMM)Wtsi}
• Genetic Background: B6JTyr;B6N-Bbx^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0036_1_B10

Data Sources

IMPC Data for Bbx

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal cranium morphology ( J:175295 )

♂

IMPC - WTSI

abnormal tooth morphology ( J:175295 )

♂

IMPC - WTSI

growth/size/body

abnormal tooth morphology ( J:175295 )

♂

IMPC - WTSI

decreased lean body mass ( J:165965 )

IMPC - WTSI

decreased body weight ( J:165965 , J:175295 )

IMPC - WTSI (J:165965)

IMPC - WTSI (J:175295)

decreased body length ( J:165965 )

IMPC - WTSI

skeleton

abnormal cranium morphology ( J:175295 )

♂

IMPC - WTSI

abnormal tooth morphology ( J:175295 )

♂

IMPC - WTSI

decreased bone mineral content ( J:165965 )

IMPC - WTSI

decreased bone mineral density ( J:165965 )

♀

IMPC - WTSI

Genotype
MGI:5790947

hm2

• Allelic Composition: Bbx^{tm1a(EUCOMM)Wtsi}/Bbx^{tm1a(EUCOMM)Wtsi}
• Genetic Background: involves: C57BL/6 * C57BL/6N
• Cell Lines: EPD0036_1_B10

cardiovascular system

decreased heart weight ( J:213427 )

craniofacial

abnormal tooth morphology ( J:213427 )

growth/size/body

abnormal tooth morphology ( J:213427 )

decreased lean body mass ( J:213427 )

decreased body length ( J:213427 )

hematopoietic system

increased IgA level ( J:213427 )

immune system

increased IgA level ( J:213427 )

skeleton

abnormal tooth morphology ( J:213427 )

decreased length of long bones ( J:213427 )

decreased bone mineral content ( J:213427 )

decreased bone mineral density ( J:213427 )

decreased bone strength ( J:213427 )