Phenotypes associated with this allele

• Allele Symbol: Socs7^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4432554
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Socs7^tm1a(EUCOMM)Wtsi/Socs7^tm1a(EUCOMM)Wtsi	B6JTyr;B6N-Socs7^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5781760
hm2	Socs7^tm1a(EUCOMM)Wtsi/Socs7^tm1a(EUCOMM)Wtsi	involves: C57BL/6 * C57BL/6N	MGI:5790953

Genotype
MGI:5781760

hm1

• Allelic Composition: Socs7^{tm1a(EUCOMM)Wtsi}/Socs7^{tm1a(EUCOMM)Wtsi}
• Genetic Background: B6JTyr;B6N-Socs7^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0021_4_A12

Data Sources

IMPC Data for Socs7

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal behavior ( J:175295 )

♂

IMPC - WTSI

vision/eye

abnormal eye size ( J:175295 )

♀

IMPC - WTSI

Genotype
MGI:5790953

hm2

• Allelic Composition: Socs7^{tm1a(EUCOMM)Wtsi}/Socs7^{tm1a(EUCOMM)Wtsi}
• Genetic Background: involves: C57BL/6 * C57BL/6N
• Cell Lines: EPD0021_4_A12

behavior/neurological

decreased response to stress-induced hyperthermia ( J:213427 )

endocrine/exocrine glands

testis degeneration ( J:213427 )

♂

homeostasis/metabolism

decreased response to stress-induced hyperthermia ( J:213427 )

reproductive system

testis degeneration ( J:213427 )

♂

vision/eye

persistent hyaloid artery ( J:213427 )

• seen in 1/4 mutants

cardiovascular system

persistent hyaloid artery ( J:213427 )

• seen in 1/4 mutants