Phenotypes associated with this allele

• Allele Symbol: Fbf1^{tm1a(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1a, Wellcome Trust Sanger Institute
• Allele ID: MGI:4432655
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbf1^tm1a(EUCOMM)Wtsi/Fbf1^tm1a(EUCOMM)Wtsi	C57BL/6N-Fbf1^tm1a(EUCOMM)Wtsi/Wtsi	MGI:5700886

Genotype
MGI:5700886

hm1

• Allelic Composition: Fbf1^{tm1a(EUCOMM)Wtsi}/Fbf1^{tm1a(EUCOMM)Wtsi}
• Genetic Background: C57BL/6N-Fbf1^{tm1a(EUCOMM)Wtsi}/Wtsi
• Cell Lines: EPD0456_2_F09

Data Sources

IMPC Data for Fbf1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

adipose tissue

increased total body fat amount ( J:211773 )

♀

IMPC - WTSI

growth/size/body

decreased lean body mass ( J:211773 )

♀

IMPC - WTSI

hematopoietic system

increased leukocyte cell number ( J:211773 )

IMPC - WTSI

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

♀

IMPC - WTSI

increased circulating insulin level ( J:211773 )

♂

IMPC - WTSI

decreased circulating cholesterol level ( J:211773 )

♂

IMPC - WTSI

decreased circulating HDL cholesterol level ( J:211773 )

♂

IMPC - WTSI

decreased circulating LDL cholesterol level ( J:211773 )

IMPC - WTSI

increased circulating alkaline phosphatase level ( J:211773 )

IMPC - WTSI

decreased circulating serum albumin level ( J:211773 )

♂

IMPC - WTSI

immune system

increased leukocyte cell number ( J:211773 )

IMPC - WTSI

limbs/digits/tail

abnormal humerus morphology ( J:211773 )

♂

IMPC - WTSI

skeleton

abnormal humerus morphology ( J:211773 )

♂

IMPC - WTSI

abnormal bone structure ( J:211773 )

♀

IMPC - WTSI

decreased bone mineral content ( J:211773 )

♀

IMPC - WTSI