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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Sec23btm1a(EUCOMM)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4432981
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sec23btm1a(EUCOMM)Wtsi/Sec23btm1a(EUCOMM)Wtsi involves: C57BL/6J * C57BL/6N MGI:5433333


Genotype
MGI:5433333
hm1
Allelic
Composition		 Sec23btm1a(EUCOMM)Wtsi/Sec23btm1a(EUCOMM)Wtsi
Genetic
Background		 involves: C57BL/6J * C57BL/6N
Cell Lines EPD0237_3_G06
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sec23btm1a(EUCOMM)Wtsi mutation (0 available); any Sec23b mutation (50 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Degeneration of pancreas, salivary, gastric and nasal glands in Sec23btm1a(EUCOMM)Wtsi/Sec23btm1a(EUCOMM)Wtsi mice

mortality/aging

endocrine/exocrine glands
nasal gland degeneration ( J:186391 )
• degeneration of the nasal glands
pancreas degeneration ( J:186391 )
• degeneration

craniofacial
nasal gland degeneration ( J:186391 )
• degeneration of the nasal glands

digestive/alimentary system

respiratory system
nasal gland degeneration ( J:186391 )
• degeneration of the nasal glands

growth/size/body
nasal gland degeneration ( J:186391 )
• degeneration of the nasal glands




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory