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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Aff3tm1a(EUCOMM)Wtsi
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4434291
Summary 2 genotypes


Genotype
MGI:5608405
hm1
Allelic
Composition		 Aff3tm1a(EUCOMM)Wtsi/Aff3tm1a(EUCOMM)Wtsi
Genetic
Background		 C57BL/6N-Aff3tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0242_2_E12
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aff3tm1a(EUCOMM)Wtsi mutation (1 available); any Aff3 mutation (53 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological

craniofacial

growth/size/body
abnormal tooth morphology ( J:211773 )
IMPC - WTSI
abnormal incisor morphology ( J:211773 )
IMPC - WTSI
abnormal snout morphology ( J:211773 )
IMPC - WTSI

homeostasis/metabolism

nervous system

skeleton

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
KINSSHIP syndrome DOID:0112383 OMIM:619297
 J:317476




Genotype
MGI:5705951
ht2
Allelic
Composition		 Aff3tm1a(EUCOMM)Wtsi/Aff3+
Genetic
Background		 C57BL/6N-Aff3tm1a(EUCOMM)Wtsi/Wtsi
Cell Lines EPD0242_2_E12
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aff3tm1a(EUCOMM)Wtsi mutation (1 available); any Aff3 mutation (53 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory