All Phenotypes Fanca<tm1a(EUCOMM)Wtsi> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Fanca^{tm1a(EUCOMM)Wtsi}
targeted mutation 1a, Wellcome Trust Sanger Institute
MGI:4434431

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fanca^{tm1a(EUCOMM)Wtsi}/Fanca^{tm1a(EUCOMM)Wtsi}	involves: C57BL/6N	MGI:5608998

Allelic Composition	Fanca^{tm1a(EUCOMM)Wtsi}/Fanca^{tm1a(EUCOMM)Wtsi}
Genetic Background	involves: C57BL/6N
Cell Lines	EPD0175_5_B09

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fanca^{tm1a(EUCOMM)Wtsi} mutation (1 available); any Fanca mutation (81 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

increased sensitivity to induced cell death ( J:188123 )

• B cells, erythroid progenitor and granulocyte-macrophage progenitor cells are more sensitive to acetaldehyde

homeostasis/metabolism

increased physiological sensitivity to xenobiotic ( J:188123 )

• B cells, erythroid progenitor and granulocyte-macrophage progenitor cells are more sensitive to acetaldehyde

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24