Phenotypes associated with this allele

• Allele Symbol: Usp12^{tm1a(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:4434551
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Usp12^tm1a(EUCOMM)Hmgu/Usp12^tm1a(EUCOMM)Hmgu	Not Specified	MGI:5782222
ht2	Usp12^tm1a(EUCOMM)Hmgu/Usp12^+	Not Specified	MGI:5782221

Genotype
MGI:5782222

hm1

• Allelic Composition: Usp12^{tm1a(EUCOMM)Hmgu}/Usp12^{tm1a(EUCOMM)Hmgu}
• Genetic Background: Not Specified
• Cell Lines: HEPD0538_7_A07

Data Sources

IMPC Data for Usp12

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased heart weight ( J:165965 )

♂

IMPC - HMGU

increased heart weight ( J:165965 )

♀

IMPC - HMGU

growth/size/body

increased heart weight ( J:165965 )

♀

IMPC - HMGU

decreased body weight ( J:165965 )

♂

IMPC - HMGU

hematopoietic system

decreased mean corpuscular hemoglobin concentration ( J:165965 )

IMPC - HMGU

decreased CD8-positive, alpha-beta T cell number ( J:165965 )

IMPC - HMGU

decreased IgA level ( J:165965 )

IMPC - HMGU

homeostasis/metabolism

decreased circulating alanine transaminase level ( J:165965 )

IMPC - HMGU

immune system

decreased CD8-positive, alpha-beta T cell number ( J:165965 )

IMPC - HMGU

decreased IgA level ( J:165965 )

IMPC - HMGU

Genotype
MGI:5782221

ht2

• Allelic Composition: Usp12^{tm1a(EUCOMM)Hmgu}/Usp12⁺
• Genetic Background: Not Specified
• Cell Lines: HEPD0538_7_A07

Data Sources

IMPC Data for Usp12

limbs/digits/tail

oligodactyly ( J:165965 )

♂

IMPC - HMGU