Phenotypes associated with this allele

• Allele Symbol: Fbxo7^{tm1a(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:4434927
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxo7^tm1a(EUCOMM)Hmgu/Fbxo7^tm1a(EUCOMM)Hmgu	involves: C57BL/6N	MGI:5317819

Genotype
MGI:5317819

hm1

• Allelic Composition: Fbxo7^{tm1a(EUCOMM)Hmgu}/Fbxo7^{tm1a(EUCOMM)Hmgu}
• Genetic Background: involves: C57BL/6N
• Cell Lines: HEPD0516_4_G01

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased pro-B cell number ( J:183053 )

• increased percentage of CD43^hiCD25^lo

increased erythroid progenitor cell number ( J:183053 )

• in bone marrow cells

abnormal proerythroblast morphology ( J:183053 )

• increase in early stage pro-erythroblasts (CD71^hiTer119^lo)

decreased erythroblast number ( J:183053 )

immune system

increased pro-B cell number ( J:183053 )

• increased percentage of CD43^hiCD25^lo